About

I am a Research Scientist at Seattle Children's Research Institute in the Center for Integrative Brain Research. My research connects how cellular and network mechanisms sustain breathing with how descending pain circuits influence respiratory control. My computational work has shown that intrinsic neuronal properties and network interactions are interdependent in respiratory rhythm generation. I now investigate how genetically defined brainstem populations coordinate pain, breathing, and motor output, with the goal of preserving analgesia while reducing respiratory suppression.

I combine data-driven biophysical models and dynamical systems analysis with electrophysiology, fiber photometry, respiratory measurements, and genetic circuit perturbations. These complementary approaches turn mechanistic predictions into experimental tests and use physiological data to refine models. I also develop PhysioMetrics and CageMetrics to make physiological and behavioral analysis more reproducible and accessible.